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The activation of a neuralizing factor in the neural plate is correlated with its homoiogenetic-inducing activity

✍ Scribed by Grunz, Horst ;Born, Jochen ;Tiedemann, Heinz ;Tiedemann, Hildegard

Book ID: 104747228
Publisher: Springer-Verlag
Year: 1986
Tongue: English
Weight: 372 KB
Volume: 195
Category: Article
ISSN: 1432-041X
DOI: 10.1007/bf00375750

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✦ Synopsis

Neural plates which are induced in the dorsal ectoderm of Triturus by the underlying mesoderm acquire, in turn, neural-inducing activity. This process is correlated with the appearance of neural-inducing activity in the microsomal fraction of the neural plate homogenate. The high-speed supernatant also acquires inducing activity after neural induction, but to a lesser extent. The experiments suggest that a masked neuralizing factor, which is already present in the ectoderm, is in part activated and exported from the inducing neural plate cells.

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