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Characterization of the neurogenic program activated by proneural factors in a neural stem cell model

✍ Scribed by D. Drechsel; C.S. Johnston; B. Berninger; M. Götz; F. Guillemot; D.S. Castro


Book ID
116552262
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
64 KB
Volume
28
Category
Article
ISSN
0736-5748

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN