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The actions of kinin antagonists on B1 and B2 receptor systems

✍ Scribed by Domenico Regoli; Guy Drapeau; Paolo Rovero; Stéphane Dion; Pedro D'Orléans-Juste; Jean Barabé

Book ID
115880333
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
352 KB
Volume
123
Category
Article
ISSN
0014-2999

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New conformationally homogeneous β-turn
New conformationally homogeneous β-turn antagonists of the human B2 kinin receptor
✍ Edith S. Monteagudo; Federico Calvani; Fernando Catrambone; Christopher I. Finch 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 241 KB

## Abstract We have designed and synthesized a conformationally homogeneous series of cyclic pentapeptides of the general structure __c__[Pro‐aa~__i__~‐𝒹‐Tic‐Oic‐aa~__i__+3~] which adopt a type‐II′ β‐turn conformation believed important for high affinity antagonism of the bradykinin (BK) B~2~ recep