𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The acoustic startle response is normal in patients with multiple system atrophy

✍ Scribed by F. Valldeoriola; J. Valls-Solé; E. Tolosa; F. A. Nobbe; J. E. Muñoz; J. Martí


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
334 KB
Volume
12
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

We investigated the acoustic startle response in eight patients with MSA and compared the results with those from a group of age matched healthy subjects. Onset latency and amplitude of the responses obtained in the orbicularis oculi, masseter and sternocleidomastoid muscles were not different in patients and control subjects. We conclude that, in spite of the pathological derangement described in brainstem reticular nuclei in MSA, the neuronal circuits mediating the auditory startle reflex are functionally preserved.


📜 SIMILAR VOLUMES


Effects of a startle on heart rate in pa
✍ Josep Valls-Solé; Misericordia Veciana; Lucia Leon; Francesc Valldeoriola 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 134 KB

The patient cooperation usually required for neurophysiological assessment of autonomic cardioregulatory function is difficult to obtain from patients with bradykinesia. A particularly interesting condition occurs in multiple system atrophy (MSA), which features both bradykinesia and autonomic dysfu

Multiple system atrophy in a patient wit
✍ Melissa J. Nirenberg; Jenny Libien; Jean-Paul Vonsattel; Stanley Fahn 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB 👁 1 views

## Abstract The cerebellar variant of multiple system atrophy (MSA‐C) has overlapping clinical features with the hereditary spinocerebellar ataxias (SCAs), but can usually be distinguished on a clinical basis. We describe a patient who developed a sporadic, late‐onset, rapidly progressive neurodege

Cell type-specific neuronal loss in the
✍ Kenta Sato; Ryuji Kaji; Sadayuki Matsumoto; Satoshi Goto 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB

## Abstract Using antibodies to calcineurin (CaN) and choline acetyltransferase (ChAT), we performed topographical and cellular immunohistochemical analysis on the posterior putamen of autopsied patients with multiple system atrophy with predominant parkinsonism (MSA‐P). We document that in these p

G2019S mutation in the leucine-rich repe
✍ Laurie J. Ozelius; Tatiana Foroud; Susanne May; Geetha Senthil; Paola Sandroni; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 56 KB 👁 1 views

## Abstract Multiple system atrophy (MSA) is characterized clinically by Parkinsonism, cerebellar dysfunction, and autonomic impairment. Multiple mutations in the __LRRK2__ gene are associated with parkinsonian disorders, and the most common one, the G2019S mutation, has been found in ∼1% of sporad