The patient cooperation usually required for neurophysiological assessment of autonomic cardioregulatory function is difficult to obtain from patients with bradykinesia. A particularly interesting condition occurs in multiple system atrophy (MSA), which features both bradykinesia and autonomic dysfu
The acoustic startle response is normal in patients with multiple system atrophy
✍ Scribed by F. Valldeoriola; J. Valls-Solé; E. Tolosa; F. A. Nobbe; J. E. Muñoz; J. Martí
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 334 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0885-3185
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✦ Synopsis
Abstract
We investigated the acoustic startle response in eight patients with MSA and compared the results with those from a group of age matched healthy subjects. Onset latency and amplitude of the responses obtained in the orbicularis oculi, masseter and sternocleidomastoid muscles were not different in patients and control subjects. We conclude that, in spite of the pathological derangement described in brainstem reticular nuclei in MSA, the neuronal circuits mediating the auditory startle reflex are functionally preserved.
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