In this communication we introduce a promising masking agent --the vinyloxycarbonyl or VOC group --for the protection of amino functions in peptide chemistry. Amino acids are easily converted to their N-VOC derivatives (l\_) in dilute aqueous base using the known vinyl chloroformate' in dioxane as t
β¦ LIBER β¦
The acetoacetyl group, an amino protective group of potential use in peptide synthesis
β Scribed by Ferruccio D'Angeli; Fernando Filira; Ernesto Scoffone
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- French
- Weight
- 181 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
We wish to report our first studies on the possibility of applying the acetoacetyl group CHzCOCHzCC-(AA), to the protection of amino groups in peptide synthesis.
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