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The absorption and excretion of the peripheral vasodilator14C-mecinarone, (14C-6809 MD) in rat, dog and man

✍ Scribed by D. R. Hawkins; K. T. Weston; L. F. Chasseaud; A. Darragh; A. O’kelly

Book ID
113006299
Publisher
Springer-Verlag
Year
1980
Tongue
English
Weight
736 KB
Volume
5
Category
Article
ISSN
0378-7966

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Absorption, distribution and excretion o
Absorption, distribution and excretion of 14C-meglumine in rats and dogs after administration of 14C-meglumine salicylate
✍ Joel F. Heeg; Gordon S. Born; Wayne V. Kessler; Stanley M. Shaw; Winthrop E. Lan 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 526 KB

Meglumine labeled with carbon-14 was administered orally as 14C-meglumine salicylate to rats and dogs to study its distribution and excretion. The compound was incompletely absorbed; that which was absorbed was rapidly excreted in the urine. Peak blood levels were about 5-10 mug/ml in rats and 2-8 m