𝔖 Bobbio Scriptorium
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The absolute configuration of echitamine iodide

✍ Scribed by H. Manohar; S. Ramaseshan

Book ID
104234998
Publisher
Elsevier Science
Year
1961
Tongue
French
Weight
108 KB
Volume
2
Category
Article
ISSN
0040-4039

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Absolute configuration and biological ac
Absolute configuration and biological activity of mequitamium iodide enantiomers
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## Abstract The enantiomers of 1‐methyl‐3‐(10__H__‐phenothiazine‐10‐ylmethyl)‐1‐azoniabicyclo[2,2,2]octane iodide (1) were prepared by chiral chromatographic resolution of the precursor mequitazine (2). The (+)‐(S)‐enantiomer 1b is 10‐fold more potent than (βˆ’)‐(R)‐enantiomer 1a as a histamine antag

The structure of echitamine
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RECEW literature 2-5 indicates awakened interest in the Constitution of the alkaloid echitamine, isolated nearly a century ago from Alstonia scholaris. Ye now point out that data accumulated elsewhere and in this Laboratory 1 Contribution 1599 from the Sterlin,