The absolute configuration of (+)-1-(3-trifluoromethylphenyl)-2-ethylamino propane [(+)-fenfluramine]
โ Scribed by A.H. Beckett; L.G. Brookes
- Publisher
- Elsevier Science
- Year
- 1968
- Tongue
- French
- Weight
- 385 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
It has been reported ( 1) that (+)-2,3-dimethylcyclopropane carboxylic acid
The l-azabicyclo[2.2. I]heptan-3-exo-ol (2) was resolved by fractional crystallisation of its hydrogen tartrate salts. The enantiomers (+)-and (-)-2 were oxidised to the ketones (-)-4 and (+)-4, respectively (Scheme). CD spectroscopy suggested that (-)-4 possesses the (IR,4S)-configuration. This abs
SINCE the absolute configuration of (+)-tartaric acid was established by Bijvoet et al., 1 the configuration of any other compound containing one or more asymmetric carbons may, in principle, be established by correlation with (+)-or (-)-tartaric acid. One of the remaining general problems of static