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Effective enzymatic resolution of rac-1-(3-trifluoromethylphenyl)propan-2-ol, precursor of fenfluramine

✍ Scribed by Nicola D'Antona; Sebastiano Mangiafico; Giovanni Nicolosi


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
66 KB
Volume
14
Category
Article
ISSN
0899-0042

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Regioselectivity of the reactions of 4,5
✍ Mohamed. R. Aouad; Nadje T. Rezki; El Sayed H. El Ahsry 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 436 KB

## Abstract magnified image A solid support under microwave (MW) irradiation without solvent allowed the synthesis of the 2,3‐epoxy‐propyl‐thioimidazole **4**, regioselectively, and prohibited its cyclization to give the imidazo[2,1‐__b__]thiazine **3** from the reaction of 4,5‐diphenylimidazole‐2