✦ LIBER ✦

The absence of p53 is critical for the induction of apoptosis by 5-aza-2′-deoxycytidine

✍ Scribed by Nieto, María; Samper, Enrique; Fraga, Mario F; González de Buitrago, Gonzalo; Esteller, Manel; Serrano, Manuel

Book ID: 110068256
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 379 KB
Volume: 23
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1207175

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

5-Aza-2′-deoxycytidine induces p21WAF ex

5-Aza-2′-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia

✍ Karin Schmelz; Mandy Wagner; Bernd Dörken; Ingo Tamm 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 1005 KB

## Abstract The DNA methylation inhibitor 5‐Aza‐2′‐deoxycytidine (5‐Aza‐CdR) has significant therapeutic value for the treatment of patients with myelodysplastic syndrome (MDS), acute myeloid leukemia (AML) and chronic myeloid leukemia (CML). The demethylating effect of 5‐Aza‐CdR has been well char

The methyltransferase inhibitor 5-aza-2-

The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells

✍ Hsi, L. C. 📂 Article 📅 2005 🏛 American Association for Cancer Research 🌐 English ⚖ 247 KB

Histone H3 lysine 27 and 9 hypermethylat

Histone H3 lysine 27 and 9 hypermethylation within the Bad promoter region mediates 5-Aza-2′-deoxycytidine-induced Leydig cell apoptosis: implications of 5-Aza-2′-deoxycytidine toxicity to male reproduction

✍ Choi, Ji-Young; Lee, Sangmi; Hwang, Soojin; Jo, Sangmee Ahn; Kim, Miji; Kim, You 📂 Article 📅 2012 🏛 Springer 🌐 English ⚖ 657 KB

Inhibition of cytidine deaminase by zebu

Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2′-deoxycytidine

✍ Maryse Lemaire; Louise F. Momparler; Noël J.-M. Raynal; Mark L. Bernstein; Richa 📂 Article 📅 2008 🏛 Springer 🌐 English ⚖ 313 KB

Induction of p53-independent apoptosis b

Induction of p53-independent apoptosis by the BH3-only protein ITM2Bs

✍ Aarne Fleischer; Angelita Rebollo 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 228 KB

Cell type-specific activation of the cyt

Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-Aza-2′-deoxycytidine

✍ Prakash Radhakrishnan; Hesham Basma; David Klinkebiel; Judith Christman; Pi-Wan 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 1015 KB