𝔖 Bobbio Scriptorium
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The “A” rule revisited: polymerases as determinants of mutational specificity

✍ Scribed by Bernard S Strauss


Book ID
117798815
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
133 KB
Volume
1
Category
Article
ISSN
1568-7864

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📜 SIMILAR VOLUMES


The ‘A rule’ of mutagen specificity: A c
✍ Dr. Bernard S. Strauss 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 717 KB

The replicative bypass of lesions in DNA and the induction of mutations by agents which react with DNA to produce damaged bases can be understood on the basis of a simple kinetic model. Bypass can be analyzed by separately considering three processes: a) addition of a base opposite a lesion, b) a pr