𝔖 Bobbio Scriptorium
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A mutation affecting the σ subunit of RNA polymerase changes transcriptional specificity

✍ Scribed by Travers, Andrew A.; Buckland, Robin; Goman, M.; Le Grice, S. S. G.; Scaife, J. G.


Book ID
109709641
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
518 KB
Volume
273
Category
Article
ISSN
0028-0836

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An E. coli mutant rpoA109 unable to support the growth of phage P2 produces DNA-dependent RNA polymerase with an altered alpha subunit. Histidine is substituted for leucine in one tryptic peptide from the mutant alpha subunit. The existence of only one rpoA gene within the E. coli chromosome is indi