The 870G>A Polymorphism of the Cyclin D1 Gene is not Associated with Breast Cancer
β Scribed by Peter Krippl; Uwe Langsenlehner; Wilfried Renner; Babak Yazdani-Biuki; Gerald Wolf; Thomas C. Wascher; Bernhard Paulweber; Werner Weitzer; Andreas Leithner; Hellmut Samonigg
- Book ID
- 111574964
- Publisher
- Springer US
- Year
- 2003
- Tongue
- English
- Weight
- 52 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract __CCND1__ mRNA is alternatively spliced to produce 2 transcripts, and the splicing pattern may be modulated by a frequent __A__870__G__ singleβnucleotide polymorphism within the conserved splice donor site of exon 4. Several studies have suggested a significant association between the _
## Abstract ## Background. Nasopharyngeal cancer (NPC) is multifactorial, and the genetic background may be a crucial etiologic factor. Cyclin D1 (CCND1) is a key regulator of the cell cycle, and its altered activity is associated with the development of cancer. ## Methods. We analyzed the A870G