## Abstract __CCND1__ mRNA is alternatively spliced to produce 2 transcripts, and the splicing pattern may be modulated by a frequent __A__870__G__ singleβnucleotide polymorphism within the conserved splice donor site of exon 4. Several studies have suggested a significant association between the _
Cyclin D1 gene polymorphism, A870G, is associated with an increased risk of salivary gland tumors in the Chinese population
β Scribed by Weijia Liu; Enxin Zhu; Ru Wang; Lihong Wang; Lu Gao; Xuesong Yang; Tingjiao Liu
- Book ID
- 108078848
- Publisher
- Elsevier
- Year
- 2011
- Tongue
- English
- Weight
- 586 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1877-7821
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## Abstract Our aim was to investigate the association of __cyclin D1__ (G870A) single nucleotide polymorphism with susceptibility to esophageal and cardiac carcinoma in a northern Chinese population. By polymerase chain reactionβsingle strand conformation polymorphism analysis, __cyclin D1__ (G870
## Abstract Cyclin D1 (CCND1) and Eβcadherin (CDH1) have been shown to be important genes of the Ξ²βcatenin/LEF pathway that is involved in colorectal carcinogenesis. However, epidemiological studies on relationship between genetic variants of these two genes and colorectal cancer (CRC) have shown i