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The +869T/C polymorphism in the transforming growth factor-β1 gene is associated with the severity and intractability of autoimmune thyroid disease

✍ Scribed by H. Yamada; M. Watanabe; T. Nanba; T. Akamizu; Y. Iwatani


Book ID
108699763
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
92 KB
Volume
151
Category
Article
ISSN
0009-9104

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The polymorphism of transforming growth
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## Background: Transforming growth factor (tgf)-beta has been shown to be a potent stimulator of collagen production by fibroblasts, and could play a role in the pathogenesis of systemic sclerosis (ssc). ## Objective: To study the possible involvement of tgf-beta1 gene polymorphism in japanese pa