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The 5-HT3 receptor antagonist zatosetron decreases the number of spontaneously active A10 dopamine neurons

✍ Scribed by Kurt Rasmussen; Marsha E. Stockton; Janet F. Czachura

Book ID: 115887228
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 556 KB
Volume: 205
Category: Article
ISSN: 0014-2999
DOI: 10.1016/0014-2999(91)90781-k

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## Abstract __Endo__‐5‐chloro‐2,3‐dihydro‐2,2‐dimethyl‐N‐(8‐methyl‐8 ‐azabicyclo‐[3.2.1.]‐oct‐3‐yl‐7‐benzofurancarboxamide‐[carbonyl‐^14^C] (Z)‐2‐butenedioate (zatosetron‐[^14^C] maleate, 1), has been prepared from 5‐chloro‐7‐bromo‐2,3‐dihydro‐2,2‐dimethylbenzofuran (5) in four radiochemical steps