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The −308 G/A polymorphism in the tumor necrosis factor-α gene is not associated with development and progression of rheumatoid arthritis in Argentinean patients

✍ Scribed by Aranda, Federico; Perés Wingeyer, Silvia D.; Schneeberger, Emilce; Valerio, María; Saint Martin, Emilia; Dal Pra, Fernando; Correa, María de los Ángeles; Citera, Gustavo; Martínez, Liliana; Mannucci, Pablo; Remondino, Graciela; de Larrañaga, Gabriela F.

Book ID: 121735924
Publisher: Wiley (Blackwell Publishing)
Year: 2014
Tongue: English
Weight: 100 KB
Volume: 19
Category: Article
ISSN: 1756-1841
DOI: 10.1111/1756-185X.12343

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## Abstract ## Objective To test whether the G‐to‐A polymorphism at position −308 in the promoter of the tumor necrosis factor α (TNFα) gene influences response to infliximab therapy in patients with rheumatoid arthritis (RA). ## Methods We genotyped 59 RA patients by polymerase chain reaction a