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The 3′ untranslated regions of the duplicated human α-globin genes are unexpectedly divergent

✍ Scribed by Michelson, Alan M.; Orkin, Stuart H.

Book ID
123288170
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
790 KB
Volume
22
Category
Article
ISSN
0092-8674

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Of the 645 Japanese subjects studied, we have identified 10 individuals heterozygous for a chromosome with the triplicated alpha-globin loci. The frequency of the triple alpha-loci was 0.008 in this population, while that of the single alpha-locus, i.e., alpha-thalassemia 2 gene, might be lower than