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The −283C/T polymorphism of the DNMT3B gene influences the progression of joint destruction in rheumatoid arthritis

✍ Scribed by Eon Jeong Nam; Kyung Hoon Kim; Seung Woo Han; Chang Min Cho; Jongmin Lee; Jae Yong Park; Young Mo Kang


Publisher
Springer
Year
2009
Tongue
English
Weight
234 KB
Volume
30
Category
Article
ISSN
0172-8172

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✍ Benedicte Mugnier; Nathalie Balandraud; Albert Darque; Chantal Roudier; Jean Rou 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 1 views

## Abstract ## Objective To test whether the G‐to‐A polymorphism at position −308 in the promoter of the tumor necrosis factor α (TNFα) gene influences response to infliximab therapy in patients with rheumatoid arthritis (RA). ## Methods We genotyped 59 RA patients by polymerase chain reaction a