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The 26S Proteasome Is Required for Estrogen Receptor-α and Coactivator Turnover and for Efficient Estrogen Receptor-α Transactivation

✍ Scribed by David M Lonard; Zafar Nawaz; Carolyn L Smith; Bert W O'Malley

Book ID
117987807
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
277 KB
Volume
5
Category
Article
ISSN
1097-2765

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## Abstract Endogenous opioid circuits are pivotal for the regulation of sexual receptivity. Treatment of mice with morphine, a preferential μ‐opioid receptor (MOR) agonist, severely attenuates lordosis. Estrogen induces internalization of MOR in cell groups of the limbic‐hypothalamic lordosis‐regu