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The 20 faces of the fourth component of complement

โœ Scribed by Andrew C. Chan; David R. Karp; Donald C. Shreffler; John P. Atkinson


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
433 KB
Volume
5
Category
Article
ISSN
0167-5699

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๐Ÿ“œ SIMILAR VOLUMES


Polymorphism of the fourth complement co
โœ Hans Grosse-Wilde; Gabriele Doxiadis; Kristine Krumbacher; Amelie Dekkers-Bijma; ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 281 KB

In man the structural genes for the HLA antigens are encoded on the short arm of chromosome 6 and constitute a linkage group with structural genes of the complement components Bf, C2, and C4 (Allen 1974, Fu et al. 1974, Rittner et al. 1975). The gene products of the whole group are characterized by

Genetic polymorphism of the fourth compo
โœ A. Marcelli-Barge; J. C. Poirier; M. Schmid; I. Deschamps; H. Lestradet; P. Prev ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 229 KB

The complement proteins, Bf, C2, C4A and C4B, are closely linked to HLA. In 74 propositi and their families, and 97 controls genotyped for HLA-A, -B, -C, DR, -Bf, a high incidence of the C4BQ0 variant was detected in the patient group (33% versus 12%, p less than 0.00001); C4BQ0 was more frequent in