The 20 faces of the fourth component of complement
โ Scribed by Andrew C. Chan; David R. Karp; Donald C. Shreffler; John P. Atkinson
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 433 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In man the structural genes for the HLA antigens are encoded on the short arm of chromosome 6 and constitute a linkage group with structural genes of the complement components Bf, C2, and C4 (Allen 1974, Fu et al. 1974, Rittner et al. 1975). The gene products of the whole group are characterized by
The complement proteins, Bf, C2, C4A and C4B, are closely linked to HLA. In 74 propositi and their families, and 97 controls genotyped for HLA-A, -B, -C, DR, -Bf, a high incidence of the C4BQ0 variant was detected in the patient group (33% versus 12%, p less than 0.00001); C4BQ0 was more frequent in