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Measurement of the second and fourth components of rat complement

✍ Scribed by H. V. Wyatt

Publisher: John Wiley and Sons
Year: 1974
Tongue: English
Weight: 202 KB
Volume: 4
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.1830040110

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## Abstract A number of tissue culture cell lines were tested for synthesis of C1, C2 and C4. Supernates from two human embryo cell lines were positive for C1 when received, but on further culturing gave only slight amounts of C1. A number of cell lines produced C2 over a long period. This producti

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In man the structural genes for the HLA antigens are encoded on the short arm of chromosome 6 and constitute a linkage group with structural genes of the complement components Bf, C2, and C4 (Allen 1974, Fu et al. 1974, Rittner et al. 1975). The gene products of the whole group are characterized by