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The 14C, 13C and 15N syntheses of MON 37500, a sulfonylurea wheat herbicide

✍ Scribed by Brad D. Maxwell; Olivier G. Boyé; Kazunari Ohta

Publisher
John Wiley and Sons
Year
2005
Tongue
French
Weight
126 KB
Volume
48
Category
Article
ISSN
0022-2135

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✦ Synopsis

14

C] and [ 13 C]MON 37500 labeled in the imidazopyridine (Im) ring system were synthesized in seven steps in an overall yield of 39 and 28%, respectively, from [2-14 C] and [2-13 C]chloroacetic acid. [ 14 C]MON 37500 labeled in the pyrimidine (Pd) ring system was synthesized from [2-14 C]diethyl malonate in four steps in 48% yield. Lastly, [ 15 N]MON 37500 was prepared in three steps in an overall yield of 28% from [ 15 N]ammonium chloride.

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