The 1,3-Diaminobenzene-Derived Aminophosphine Palladium Pincer Complex {C6H3[NHP(piperidinyl)2]2Pd(Cl)} – A Highly Active Suzuki–Miyaura Catalyst with Excellent Functional Group Tolerance

✍ Scribed by Jeanne L. Bolliger; Christian M. Frech

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 204 KB
• Volume: 352
• Category: Article
• ISSN: 1615-4150
• DOI: 10.1002/adsc.200900848

✦ Synopsis

Abstract

The rapidly prepared 1,3‐diaminobenzene‐derived aminophosphine pincer complex {C~6~H~3~[NHP(piperidinyl)~2~]~2~Pd(Cl)} (1) is an effective Suzuki catalyst with excellent functional group tolerance. Side‐product formations, such as homocoupling, debromation or protodeboration have only rarely been detected and if so, were in all cases below the 5% level. The presented reaction protocol is universally applicable. Experimental observations indicate that palladium nanoparticles are the catalytically active form of 1.