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Thalidomide destabilizes cyclooxygenase-2 mRNA by inhibiting p38 mitogen-activated protein kinase and cytoplasmic shuttling of HuR

✍ Scribed by Soo Hyun Jin; Won Ho Kim; Tae Il Kim; Kyung Min Yang; Sung Kwan Shin; Sang Kil Lee; Soo Jin Park; Chang Hwan Choi; Won Jae Lee


Book ID
119426911
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
184 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Indian hedgehog (Ihh) is produced by growth plate pre‐hypertrophic chondrocytes, and is an important regulator of endochondral ossification. However, little is known about the regulation of Ihh in chondrocytes. We have examined the role of integrins and mitogen‐activated protein (MAP) k