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Thalidomide destabilizes cyclooxygenase-2 mRNA by inhibiting p38 mitogen-activated protein kinase and cytoplasmic shuttling of HuR

✍ Scribed by Soo Hyun Jin; Tae Il Kim; Kyoung Min Yang; Won Ho Kim


Book ID
113586650
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
555 KB
Volume
558
Category
Article
ISSN
0014-2999

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## Abstract Indian hedgehog (Ihh) is produced by growth plate pre‐hypertrophic chondrocytes, and is an important regulator of endochondral ossification. However, little is known about the regulation of Ihh in chondrocytes. We have examined the role of integrins and mitogen‐activated protein (MAP) k