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Th17 cells: positive or negative role in tumor?

✍ Scribed by Yuqiang Ji; Wanggang Zhang

Book ID: 105967756
Publisher: Springer-Verlag
Year: 2010
Tongue: English
Weight: 261 KB
Volume: 59
Category: Article
ISSN: 0340-7004
DOI: 10.1007/s00262-010-0849-6

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## Abstract Tissue factor is the prime initiator of blood coagulation. Expression of tissue factor in tumor endothelial cells leads to thrombus formation, occlusion of vessels and development of hemorrhagic infarctions in the tumor tissue, often followed by regression of the tumor. Tumor cells prod