Current Views on the Roles of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis
β Scribed by El-behi, Mohamed; Rostami, Abdolmohamad; Ciric, Bogoljub
- Book ID
- 107380720
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 288 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1557-1890
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## Abstract Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease with similarities to multiple sclerosis (MS). It has been suggested that relapses of EAE and MS may be associated with, and even driven by, T cells specific for novel epitopes that are primed during
## Abstract Compared with other Tβhelper subsets, Th17 cell numbers are very low in human blood but become elevated in chronic inflammatory diseases. In this study, we investigated mechanisms that may explain the frequent involvement of Th17 cells in autoimmune diseases such as uveitis. We compared