TGFbeta inducible early gene (TIEG) is a novel Krüppel-like transcriptional repressor that was recently shown to increase the activity of the TGFbeta/Smad signal transduction pathway by relieving negative feedback through repression of the inhibitory Smad7. Interestingly, while Smad7 is required for
TGFβ inducible early gene enhances TGFβ/Smad-dependent transcriptional responses
✍ Scribed by Johnsen, Steven A; Subramaniam, Malayannan; Janknecht, Ralf; Spelsberg, Thomas C
- Book ID
- 110066850
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 188 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0950-9232
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