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TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells

✍ Scribed by Elias Utreras, Michaela Prochazkova, Anita Terse, Jacklyn Gross…

Book ID
120694743
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
711 KB
Volume
9
Category
Article
ISSN
1744-8069

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## Transforming growth factor-␤1 (TGF-␤) inhibits cell-cycle progression of many types of cells by arresting them in G 1 /S phase through inhibition of the active cyclin-Cdk complexes that lead to inhibition of Rb phosphorylation. In gastriccancer cells, SNU16, TGF-␤ treatment induced enhanced exp