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TFPI-2 Downregulates Multidrug Resistance Protein in 5-FU-Resistant Human Hepatocellular Carcinoma BEL-7402/5-FU Cells

✍ Scribed by Lu, Fei; Hou, Yong-Qiang; Song, Ying; Yuan, Zheng-Jiang


Book ID
118752575
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
487 KB
Volume
296
Category
Article
ISSN
1932-8486

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## Abstract In this study, oroxylin A showed strong reversal potency in BEL7402/5‐FU cells and the reversal fold (RF) reached 4.69. Simultaneously, rhodamine‐123 accumulation assay and flow cytometry analysis demonstrated oroxylin A could increase drug accumulation. When combined with oroxylin A, 5