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TFA-catalyzed C–N bond activation of enamides with indoles: efficient synthesis of 3,3-bisindolylpropanoates and other bisindolylalkanes

✍ Scribed by Xu, Hai-Yan; Zi, You; Xu, Xiao-Ping; Wang, Shun-Yi; Ji, Shun-Jun


Book ID
118228870
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
403 KB
Volume
69
Category
Article
ISSN
0040-4020

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## Abstract An efficient oxidative cross‐coupling reaction between 1,3‐diarylpropenes and indoles in the presence of palladium chloride was achieved with 2,3‐dichloro‐5,6‐dicyanoquinone (DDQ) as oxidant. The reaction afforded 1,3‐diphenylallylindoles in moderate to high yields under mild conditions