✦ LIBER ✦
Efficient Palladium-Catalyzed Oxidative Indolation of Allylic Compounds with DDQ via sp3 CH Bond Activation and Carbon-Carbon Bond Formation Under Mild Conditions
✍ Scribed by Hanjie Mo; Weiliang Bao
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 169 KB
- Volume
- 351
- Category
- Article
- ISSN
- 1615-4150
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✦ Synopsis
Abstract
An efficient oxidative cross‐coupling reaction between 1,3‐diarylpropenes and indoles in the presence of palladium chloride was achieved with 2,3‐dichloro‐5,6‐dicyanoquinone (DDQ) as oxidant. The reaction afforded 1,3‐diphenylallylindoles in moderate to high yields under mild conditions, thus providing a novel methodology to synthesize the respective products.