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Tetrahydroepoxides and diol epoxides of benz[c]acridine

✍ Scribed by Subodh Kumar; Roland E. Lehr

Book ID
104219652
Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
211 KB
Volume
23
Category
Article
ISSN
0040-4039

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✦ Synopsis

The chemical synthesis and NMR characterization of the benzo ring tetrahydro-and diol epoxides of the carcinogen benz[cIacridine are described.

Chemical synthesis of the various positional and diastereomeric diol epoxides of selected polycyclic aromatic hydrocarbons (PAH) for biological studies has been an essential factor in

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High-performance liquid chromatography on an ion-exchange column for the separation of methyl-substituted benz[c]acridines was investigated. A cation-exchange column (Partisil 10 SCX) was used with acetonitrilee0.001 M (NH&HP04 as the mobile phase. The retention times depended on the composition of