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Testing the reverse transcriptase model of somatic mutation

✍ Scribed by Stephen Z Sack; Philip D Bardwell; Matthew D Scharff

Book ID
117325336
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
155 KB
Volume
38
Category
Article
ISSN
0161-5890

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Thymidine analogue reverse transcriptase
Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure
✍ Anne-GeneviΓ¨ve Marcelin; Constance Delaugerre; Marc Wirden; Pedro Viegas; Anne S πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 71 KB

During ZDV or d4T exposure, mutations at codons 41, 67, 70, 210, 215, and 219 can be selected and were named thymidine analogue mutations (TAMs). Some previous results suggested that different TAMs patterns could exist and that the kind of TAMs pattern could influence the virological response to som