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Does the M184V resistance mutation in reverse transcriptase reduce HIV transmission?

✍ Scribed by D Turner


Book ID
111063777
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
38 KB
Volume
12
Category
Article
ISSN
1464-2662

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## Abstract The K65R mutation in HIV‐1 reverse transcriptase (RT) can be selected by the RT inhibitors tenofovir (TDF), abacavir (ABC), and didanosine (DDI). Recently, in vitro studies have shown that K65R is selected in tissue culture more rapidly with subtype C than subtype B viruses. The prevale