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Testing method for mechanical properties of fibrin glue

✍ Scribed by Georg N. Duda; Edmund Y. S. Chao; John J. Grabowski; Howard F. Taswell

Publisher
Wiley (John Wiley & Sons)
Year
1993
Tongue
English
Weight
659 KB
Volume
4
Category
Article
ISSN
1045-4861

No coin nor oath required. For personal study only.

✦ Synopsis

A testing method was developed to evaluate the mechanical properties of a fibrin adhesive in an effort to correlate mechanical strength to fibrinogen content. Autologous fibrin adhesives with varying fibrinogen content were loaded to failure in shear using a mechanical testing machine. The method developed was capable of distinguishing a mechanical strength difference among the three fibrin sample lots used in the study. A number of parameters were evident that could lead to testing variability. The development of a more sophisticated component delivery system would greatly reduce the variability of these parameters and thus, the product reliability. Ultimately, the information gathered from the current and future studies will form a type of quality control standard to directly correlate the percentage of fibrinogen in a particular sample to its adhesive performance.@ 1993 John Wiley & Sons, Inc.

We wish to thank Larry Berglund and Fred Schultz for their technical expertise and assistance in completing this study.

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