Test No. 451: Carcinogenicity Studies

Translations on Africa Nos. 444, 445, 44

📁 Translations on Africa Nos. 444, 445, 446, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 459, 460, 461, 462, 463

✍ Joint Publications Research Service (JPRS) 📂 Library 📅 1966 🏛 U.S. Department of Commerce, Clearinghouse for Fed 🌐 English

This serial publication contains translations selected from various foreign-language sources on all countries of Africa except Egypt, on the specific subjects reflected in each table of contents. Complete bibliographic information accompanies each article.

Test no. 451: carcinogenicity studies

📁 Test no. 451: carcinogenicity studies

✍ coll. 📂 Library 📅 2009 🏛 OECD Publishing 🌐 English

The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of administration. This Test Guideline is intended pr

Test no. 451: carcinogenicity studies

📁 Test no. 451: carcinogenicity studies

✍ coll. 📂 Library 📅 2009 🏛 OECD Publishing 🌐 English

The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of administration. This Test Guideline is intended pr

Test No. 453: Combined Chronic Toxicity/

📁 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

✍ coll. 📂 Library 📅 2009 🏛 OECD Publishing 🌐 English

The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for this study. For rodents, each dose group and con

Guidance Document 116 on the Conduct and

📁 Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 : Second edition.

✍ OECD 📂 Library 📅 2014 🏛 [publisher not identified] 🌐 English

Test No. 452: Chronic Toxicity Studies

📁 Test No. 452: Chronic Toxicity Studies

✍ OECD 📂 Library 📅 2009 🏛 OECD Publishing 🌐 English

The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both sexes should be used. For rodents, at least 20 ani