Test No. 452: Chronic Toxicity Studies

✍ Scribed by OECD

Publisher: OECD Publishing
Year: 2009
Tongue: English
Leaves: 16
Series: OECD Guidelines for the Testing of Chemicals Section 4
Category: Library

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✦ Synopsis

The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both sexes should be used. For rodents, at least 20 animals per sex per group should normally be used at each dose level, while for non-rodents a minimum of 4 per sex per group Read more...

✦ Subjects

Environment

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