A new technique for the conversion of 2-acetylaminofluorene and several ring-hydroxylated metabolites to mono-and di-tert.butyldimethylsilyl derivatives was developed to permit their analysis by gas chromatography-mass spectrometry in order to quantify the metabolism of 2-acetylaminofluorene incubat
tert.-Butyldimethylsilylation of ethyl 3-bromo-2-hydroxyiminopropanoate and analysis of the products by gas chromatography-mass spectrometry
β Scribed by John Leveson Gower; Gerald D. Risbridger; Michael J. Redrup
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 179 KB
- Volume
- 299
- Category
- Article
- ISSN
- 1873-3778
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π SIMILAR VOLUMES
A method for analysis of aliphatic aldehydes in biological samples is described. Cyclohexanone is added as internal standard and the samples are treated with hydroxylamine and perchloric acid. The oximes are extracted and converted to the oxime-tert-butyldimethylsilyl derivatives, which are quantita
## Abstract The aim of the present study was to setβup a Fast gas chromatography/mass spectrometry method for the analysis of cholesterol oxidation products (COPs). A silylated mixture of seven oxysterol standards was injected into a Fast GC/MS system. A capillary GC column (10βmΓ0.1βmm internal di