Terminal deletion of 1p36
β Scribed by Lisa G Shaffer; Heidi A Heilstedt
- Book ID
- 117279257
- Publisher
- The Lancet
- Year
- 2001
- Tongue
- English
- Weight
- 67 KB
- Volume
- 358
- Category
- Article
- ISSN
- 0140-6736
No coin nor oath required. For personal study only.
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At least 70% of human neuroblastomas display cytogenetically visible aberrations in the short arm of chromosome I . We have used a panel of probes detecting polymorphic D N A loci, most of which were derived from a library of microdissected distal I p chromosome fragments, to compare the hybridizati
Nonradioactive in situ hybridization (NISH) on sections of paraffin-embedded neuroblastoma tissue was performed to evaluate numerical and structural aberrations of chromosome I. Two biotinylated probes specific for the heterochromatic (D I Z I) and subtelomeric regions of chromosome I (DIS32) were u