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Teratogenic effects of antiepileptic drugs

✍ Scribed by Torbjörn Tomson; Dina Battino


Book ID
116880418
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
103 KB
Volume
17
Category
Article
ISSN
1059-1311

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## Abstract **BACKGROUND:** Although valproic acid (VPA) is used extensively for treating various kinds of epilepsy, it causes hepatotoxicity and teratogenicity. In an attempt to develop a more potent and safer second generation to VPA drug, the amide derivatives of the tetramethylcyclopropyl VPA a