✦ LIBER ✦

Terahertz-Pulsed Spectroscopy and Imaging in Pharmaceutical Setting

✍ Scribed by J. Axel Zeitler; Philip F. Taday; David A. Newnham; Michael Pepper; Keith C. Gordon; Thomas Rades

Publisher: John Wiley and Sons
Year: 2007
Weight: 11 KB
Volume: 38
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200727273

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Terahertz Pulsed Sp

ChemInform Abstract: Terahertz Pulsed Spectroscopy and Imaging for Pharmaceutical Applications

✍ Yao-Chun Shen 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 18 KB 👁 1 views

Using terahertz pulsed spectroscopy to q

Using terahertz pulsed spectroscopy to quantify pharmaceutical polymorphism and crystallinity

✍ Clare J. Strachan; Philip F. Taday; David A. Newnham; Keith C. Gordon; J. Axel Z 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 227 KB

Terahertz pulsed spectroscopy (TPS) is a new technique that is capable of eliciting rich information when investigating pharmaceutical materials. In solids, it probes long-range crystalline lattice vibrations and low energy torsion and hydrogen bonding vibrations. These properties make TPS potential

Relaxation and crystallization of amorph

Relaxation and crystallization of amorphous carbamazepine studied by terahertz pulsed spectroscopy

✍ J. Axel Zeitler; Philip F. Taday; Michael Pepper; Thomas Rades 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 483 KB

At the example of carbamazepine the crystallization of a small organic molecule from its amorphous phase was studied using in situ variable temperature terahertz pulsed spectroscopy (TPS). Even though terahertz spectra of disordered materials in the glassy state exhibit no distinct spectral features

Nondestructive analysis of tablet coatin

Nondestructive analysis of tablet coating thicknesses using terahertz pulsed imaging

✍ Anthony J. Fitzgerald; Bryan E. Cole; Philip F. Taday 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB

An understanding of the finished structure of complex pharmaceutical coating is becoming desirable, because tablet coatings are now one of the preferred routes to control the release of active pharmaceutical ingredients. There are few nondestructive techniques capable of examining the coatings of co

Process analytical technology (PAT): Qua

Process analytical technology (PAT): Quantification approaches in terahertz spectroscopy for pharmaceutical application

✍ Huiquan Wu; Edwin J. Heilweil; Ajaz S. Hussain; Mansoor A. Khan 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 215 KB

Terahertz (THz) spectroscopy and chemometric analysis of resultant absorption spectra in the 30-500 cm(-1) range has been applied to perform quantitative determination of both active ingredient and excipient concentrations of tablets. Tests were performed on a series of tablets composed of various c

Monitoring the film coating unit operati

Monitoring the film coating unit operation and predicting drug dissolution using terahertz pulsed imaging

✍ Louise Ho; Ronny Müller; Keith C. Gordon; Peter Kleinebudde; Michael Pepper; Tho 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 344 KB

Understanding the coating unit operation is imperative to improve product quality and reduce output risks for coated solid dosage forms. Three batches of sustained-release tablets coated with the same process parameters (pan speed, spray rate, etc.) were subjected to terahertz pulsed imaging (TPI) a