✦ LIBER ✦

Ten years' experience with enteral levodopa infusions for motor fluctuations in Parkinson's disease

✍ Scribed by Nadir Syed; John Murphy; Thomas Zimmerman Jr.; Margery H. Mark; Jacob I. Sage

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 294 KB
Volume: 13
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870130222

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We report our long‐term experience using enteral levodopa infusions in 22 patients with Parkinson's disease and severe motor fluctuations. Amelioration of intractable dyskinesias was the most important factor that determined whether patients chose to continue using the infusion pump system. Mechanical and physical problems associated with enteral access were the most common reasons for which patients discontinued pump use. Nearly all patients continued to have dramatically increased on time for the duration of follow up, suggesting that technically less‐cumbersome systems that provide continuous dopaminergic stimulation are worthwhile and should be developed.

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