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Temporally regulated assembly of a dynamic signaling complex associated with the activated TCR

✍ Scribed by Sonia Pacini; Silvia Valensin; John L. Telford; John Ladbury; Cosima T. Baldari


Book ID
101382386
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
386 KB
Volume
30
Category
Article
ISSN
0014-2980

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Assembly of the TCR/CD3 complex: CD3ϵ/δ
✍ Ester San José; Almudena G. Sahuquillo; Rafael Bragado; Balbino Alarcón 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface in a coordinate fashion after assembly in the endoplasmic reticulum (ER). The TCR/CD3 complex is assembled after a series of pairwise interactions involving the formation of dimers of CD3 epsilon with either CD3