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Temporal properties of the hemodynamic response in functional MRI

✍ Scribed by F. Kruggel; D.Y. von Cramon

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
587 KB
Volume
8
Category
Article
ISSN
1065-9471

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✦ Synopsis

Today, most studies of cognitive processes using functional magnetic resonance imaging (fMRI) adopt an event-related experimental design. Highly flexible stimulation settings require new statistical models where not only the activation amount, but also the time course of the measured hemodynamic response is analyzed. It is possible to obtain statistically valid descriptions of single hemodynamic responses from a robust nonlinear estimation procedure. Focus is placed on the temporal behaviour of the hemodynamic response: relative temporal order, changes induced by modification of the experimental context, and interindividual differences. Example analyses from recent fMRI studies underline the usefulness of this approach. Hum.

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