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Temperature sensitive mutants of an avian sarcoma virus

โœ Scribed by Toyoshima, Kumao; Vogt, Peter K.

Book ID
123357654
Publisher
Elsevier Science
Year
1969
Tongue
English
Weight
190 KB
Volume
39
Category
Article
ISSN
0042-6822

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T h e DNA polymerase ("reverse transcriptase") has been isolated from virions of two temperature-sensitive Rous sarcoma virus mutants (ts335 a n d ts337). These mutants are defective a t a n early stage of both growth a n d transformation. The purified polymerase is three-fold more rapidly inactivat