β Scribed by Kay Hamacher
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
This work presents a chemometric classification for a set of 24 known HIV-1 protease inhibitors, based on two pattern recognition methods widely used in quantitative structure-activity (QSAR) studies: soft independent modeling of class analogy (SIMCA) and Kth nearest neighbors (KNN) with the aim of
Polyoxometalates (POMs) are interesting biomedical agents due to their versatile anticancer and antiviral properties, such as remarkable anti-HIV activity. Although POMs are tunable and easily accessible inorganic drug prototypes in principle, their full potential can only be tapped by enhancing the
Forty-eight methanol and aqueous extracts from Sudanese plants were screened for their inhibitory activity on viral replication. Nineteen extracts showed inhibitory effects on HIV-induced cytopathic effects (CPE) on MT-4 cells. The extracts were further screened against HIV-1 protease (PR) using an