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Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

✍ Scribed by Sundquist, Wesley I.; Klug, Aaron


Book ID
109762154
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
587 KB
Volume
342
Category
Article
ISSN
0028-0836

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Guanine quadruplex formation by RNA/DNA
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## Abstract Using circular dichroism spectroscopy, gel electrophoresis, and ultraviolet absorption spectroscopy, we have studied quadruplex folding of RNA/DNA analogs of the __Oxytricha__ telomere fragment, G~4~T~4~G~4~, which forms the well‐known basket‐type, antiparallel quadruplex. We have subst