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Telomeric associations and consistent growth factor overexpression detected in giant cell tumor of bone

✍ Scribed by Herbert S. Schwartz; Merlin G. Butler; Robert B. Jenkins; Duncan A. Miller; Harold L. Moses


Book ID
119104961
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
853 KB
Volume
56
Category
Article
ISSN
0165-4608

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## Abstract Giant cell tumor of bone (GCTB) is a benign but locally aggressive tumor with metastatic potential. We performed cytogenetic analysis on 101 GCTB from 92 patients. Karyotypes were obtained from 95 tumors, 47 of which had clonal aberrations. The majority of the cytogenetically abnormal G